An expert discusses how cortisol, a vital hormone regulating stress, metabolism, and the sleep-wake cycle, can lead to a complex range of symptoms when elevated—beyond classic Cushing syndrome—highlighting the importance of recognizing subtle signs such as resistant hypertension, fatigue, and poorly controlled diabetes for early diagnosis and treatment.

An expert discusses the steps a patient should take if they suspect hypercortisolism and how they can advocate for screening with their health care provider.

Clinicians across specialties explain how health misinformation is reshaping patient decisions, delaying care and undermining trust.

Living with psoriatic disease and diabetes, Brian found new confidence through weight loss and improved symptom management.

Actor Anthony Anderson shares how losing his father to diabetes and facing his own diagnosis turned him into a passionate patient advocate.

A panelist discusses how cortisol excess often goes undetected in patients with poorly controlled type 2 diabetes and resistant hypertension, emphasizing the importance of proactive screening to improve diagnosis and treatment outcomes and reduce long-term complications.

A panelist discusses how abnormal dexamethasone suppression test (DST) results may indicate cortisol overproduction, emphasizing the importance of ruling out false-positive and false-negative results before proceeding to adrenal imaging for accurate diagnosis and targeted treatment.

Robert Califf, M.D., urges patients and those at risk of illness to find trustworthy health care providers who can help them navigate a fragmented medical system.

A panelist discusses how the dexamethasone suppression test (DST) serves as a simple, cost-effective screening tool for cortisol excess, with proper timing and interpretation of both cortisol and dexamethasone levels being essential for accurate diagnosis and guiding further evaluation.

A panelist discusses how the dexamethasone suppression test (DST), particularly the 1-mg overnight test and 2-day low-dose test, is used to screen for cortisol excess, with the 2-day test offering higher specificity and the choice of test depending on the clinical context and patient symptoms.

A panelist discusses how screening for excess cortisol in individuals with poorly controlled type 2 diabetes can uncover a hidden hormonal driver of insulin resistance and poor glycemic control, enabling earlier intervention and more targeted, effective treatment to reduce long-term complications.

A panelist discusses how screening for excess cortisol in individuals with poorly controlled type 2 diabetes can uncover a hidden hormonal driver of insulin resistance and poor glycemic control, enabling earlier intervention and more targeted, effective treatment to reduce long-term complications.

Maddison Saalinger, MS, RDN, explains that there’s no one-size-fits-all “diabetes diet” — just a nutrient-dense, well-balanced approach to eating.

An expert discusses how excess cortisol disrupts blood sugar regulation and promotes insulin resistance, making type 2 diabetes more difficult to manage while also driving visceral fat accumulation and increasing long-term risks for metabolic and cardiovascular diseases.

An expert discusses how cortisol, a vital hormone regulating stress, metabolism, and the sleep-wake cycle, can lead to a complex range of symptoms when elevated—beyond classic Cushing syndrome—highlighting the importance of recognizing subtle signs such as resistant hypertension, fatigue, and poorly controlled diabetes for early diagnosis and treatment.

An expert discusses the steps a patient should take if they suspect hypercortisolism and how they can advocate for screening with their health care provider.